Artificial and natural nucleic acid self assembling systems
نویسندگان
چکیده
ARTIFICIAL AND NATURAL NUCLEIC ACIDSELF ASSEMBLING SYSTEMS byMARCUS WOODAugust 2011Advisor: Dr. John SantaLucia, Jr., Dr. David RuedaMajor: ChemistryDegree: Doctor of Philosophy Nucleic acids are good candidates for nanomachine construction. They participatein all the processes of life, and so can function as structural building blocks and dynamiccatalysts. However, to use nucleic acids as nanomachines, a better understanding of theirmaterial properties, how to design structures using them, and their dynamics is needed.We have tried to address these issues, in a small way, with nucleic acid force fielddevelopment, an attempt at nanostructural design and synthesis using DNA, and a studyof the RNA/protein regulatory dynamics of the tryptophan regulatory attenuation protein.
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